Biochemistry: Dressing the SOD

Aerosolized manganese SOD decreases hyperoxic pulmonary injury in primates. I. Physiology and biochemistry.

Prolonged hyperoxia causes lung injury and respiratory failure secondary to oxidative tissue damage mediated, in part, by the superoxide anion. We hypothesized that aerosol treatment with recombinant human manganese superoxide dismutase (rhMnSOD) would attenuate hyperoxic lung damage in primates. Adult baboons were anesthetized and ventilated with 100% oxygen for 96 h or until death. Six animal...

The 15th Iranian National Congress of Biochemistry & 6th International Congress of Biochemistry and Molecular Biology

Dressing the Giant Magnon

We apply the dressing method to construct new classical string solutions describing various scattering and bound states of magnons. These solutions carry one, two or three SO(6) charges and correspond to multi-soliton configurations in the generalized sineGordon models.

The Ideal Haemostatic Dressing

Email: [email protected] Introduction The problem of haemorrhage is well recognised by the deploying military medical community. In 1970 Maughon, after examining the combat deaths of 2600 American servicemen in Vietnam, articulated the simple requirement that more be done on the battlefield to prevent death from haemorrhage: “The striking feature was to see healthy young Americans with a...

Differential expression of EC-SOD, Mn-SOD and CuZn-SOD in rat lung exposed to crystalline silica.

Superoxide dismutases (SODs) are antioxidant enzymes that catalyze the dismutation of superoxide into hydrogen peroxide. There are 3 kinds of isozymes: extracellular superoxide dismutase (EC-SOD), manganese-containing superoxide dismutase (Mn-SOD) and copper- and zinc-containing superoxide dismutase (CuZn-SOD). To examine the expression of SOD isozymes in lungs injured by crystalline silica, we...